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  Epub 2018 Mar 19  

Systolic pulmonary artery pressure assessed during routine exercise Doppler echocardiography: insights of a real-world setting in patients with elevated pulmonary pressures

Susanne Korff, Patricia Enders-Gier, Lorenz Uhlmann, Matthias Aurich, Sebastian Greiner, Kristóf Hirschberg, Hugo A. Katus, Derliz Mereles

Pulmonary hypertension is a marker of disease severity. Exercise Doppler echocardiography (EDE) has proven to be feasible and reliable to assess pulmonary pressure. Increase in systolic pulmonary artery pressure (sPAP) has diagnostic and prognostic value in controlled studies. However, its value when assessed during routine examination in patients with cardiopulmonary diseases and resting sPAP?>?35 mmHg is not clearly defined. Clinical documentation and offline reevaluation of digitally stored EDE examinations of patients . . .
The International Journal of Cardiovascular Imaging 2018


  Epub 2018 Feb 21  

Unidimensional Longitudinal Strain: A Simple Approach for the Assessment of Longitudinal Myocardial Deformation by Echocardiography

Matthias Aurich, Patrick Fuchs, Matthias Müller-Hennessen, Lorenz Uhlmann, Matthias Niemers, Sebastian Greiner, Tobias Täger, Kristóf Hirschberg, Philipp Ehlermann, Benjamin Meder, Lutz Frankenstein, Evangelos Giannitsis, Hugo A. Katus, Derliz Mereles

Impaired left ventricular (LV) longitudinal function (LF) is a known predictor of cardiac events in patients with heart failure, but two-dimensional strain imaging, the reference method to measure myocardial deformation, is not always feasible or available. Therefore, reliable and reproducible alternatives are needed. The aim of the present study was to evaluate unidimensional longitudinal strain (ULS) as a simple echocardiographic parameter for the assessment of LV LF. Two hundred two patients with dilated cardiomyopathy . . .
Journal of the American Society of Echocardiography 2018


  Epub 2018 Jan 19  

Prognostic relevance of elevated pulmonary arterial pressure assessed non-invasively: Analysis in a large patient cohort with invasive measurements in near temporal proximity

Sebastian Greiner, Andreas Jud, Matthias Aurich, Christoph Geisenberger, Lorenz Uhlmann, Thomas Hilbel, Meinhard Kieser, Hugo A. Katus, Derliz Mereles

The clinical relevance of non-invasively derived pulmonary arterial pressure (PAP) by Doppler echocardiography (DE) has been questioned in the past. However, transthoracic echocardiography is used as a cornerstone examination for patients with dyspnea and suspected pulmonary hypertension (PH). This study aimed to evaluate the prognostic value of non-invasive assessed PAP in a large population of patients with known or suspected cardiopulmonary disease. The analyses are based on data of patients of a tertiary cardiology center that received right heart catheterization (RHC) as well as non-invasively assessed PAP by DE within five days, and includes serological and clinical parameters in a retrospective follow-up for up to eight years . . .
PLoS One 2018


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