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  Epub 2019 Apr 3  

A closer look at right ventricular 3D volume quantification by transthoracic echocardiography and cardiac MRI

Sebastian Greiner, Florian André, Melissa Heimisch, Matthias Aurich, Henning Steen, Hugo A. Katus, Derliz Mereles

To compare right ventricular volumetry using state-of-the-art three-dimensional transthoracic echocardiography (3DE) and cardiac magnetic resonance imaging near-simultaneously in a clinical setting. Forty-seven consecutive patients received comprehensive echocardiography including 3DE within 30 minutes of CMR. RV volumetry was performed offline with semi-automated 3D endocardial border tracing . . .
Clinical Radiology 2019


  Epub 2019 Mar 7  

Pathophysiological background and prognostic implication of systolic aortic root motion in non-ischemic dilated cardiomyopathy

Matthias Aurich, Matthias Niemers, Patrick Fuchs, Sebastian Greiner, Matthias Müller-Hennessen, Lorenz Uhlmann, Evangelos Giannitsis, Philipp Ehlermann, Benjamin Meder, Hugo A. Katus, Derliz Mereles

Recordings of aortic root movement represent one of the first accomplishments of ultrasound in medicine and mark the beginning of functional cardiac imaging. However, the underlying mechanism is not completely understood. Since the aortic root is directly connected to the cardiac skeleton we hypothesize, that the amplitude of systolic aortic root motion (SARM) may be mainly caused by displacement of the cardiac base towards the apex . . .
Scientific Reports 2019


  Epub 2018 Sep 12  

Prognostic relevance of the right ventricular myo-mechanical index (RV-MMI) in patients with precapillary pulmonary hypertension

Sebastian Greiner, Ferdinand Goppelt, Matthias Aurich, Hugo A. Katus, Derliz Mereles

The aim of the prospective New-RV study was to evaluate a parameter for non-invasive quantification of right ventricular (RV) dysfunction in patients with precapillary pulmonary hypertension (PH) that yields prognostic information and is applicable in daily clinical routine. Sixty-five consecutive patients with precapillary PH under guideline conform therapy (43 women, 22 men) underwent clinical assessment, serological testing, as well as a comprehensive transthoracic echocardiography . . .
Open Heart 2018


  Epub 2018 Mar 19  

Systolic pulmonary artery pressure assessed during routine exercise Doppler echocardiography: insights of a real-world setting in patients with elevated pulmonary pressures

Susanne Korff, Patricia Enders-Gier, Lorenz Uhlmann, Matthias Aurich, Sebastian Greiner, Kristóf Hirschberg, Hugo A. Katus, Derliz Mereles

Pulmonary hypertension is a marker of disease severity. Exercise Doppler echocardiography (EDE) has proven to be feasible and reliable to assess pulmonary pressure. Increase in systolic pulmonary artery pressure (sPAP) has diagnostic and prognostic value in controlled studies. However, its value when assessed during routine examination in patients with cardiopulmonary diseases and resting sPAP?>?35 mmHg is not clearly defined. Clinical documentation and offline reevaluation of digitally stored EDE examinations of patients . . .
The International Journal of Cardiovascular Imaging 2018


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